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静态与对话式AI生成消息对结直肠癌筛查意愿的影响:一项随机对照试验

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一项预注册随机对照试验纳入915名45-75岁、从未完成结直肠癌筛查的美国成年人,随机分为无消息对照、专家撰写患者材料、单条AI生成消息和动机式访谈聊天机器人四组,所有参与者需在分配条件下停留至少三分钟,两个AI组依据自报年龄和性别进行内容定制。结果显示,两种AI干预均使粪便检测意愿提升超过12分(12.9-13.8/100),而专家材料仅提升7.5分。

AI推荐理由 预注册随机对照试验(n=915,45-75岁未做过结直肠癌筛查的美国成年人),对比无消息对照、专家撰写材料、单条AI生成消息和动机式访谈聊天机器人四种条件,AI两组均使粪便检测意愿提升超过12分(12.9-13.8/100),专家材料仅提升7.5分。提供了LLM在临床说服场景的可验证量化证据,但摘要被截断,未给出完整统计显著性与效应量细节,且样本限于美国特定人群,外推需谨慎。

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Computer Science > Computers and Society arXiv:2507.08211 (cs) [Submitted on 10 Jul 2025] Title:Effect of Static vs. Conversational AI-Generated Messages on Colorectal Cancer Screening Intent: a Randomized Controlled Trial Authors:Neil K. R. Sehgal, Manuel Tonneau, Andy Tan, Shivan J. Mehta, Alison Buttenheim, Lyle Ungar, Anish K. Agarwal, Sharath Chandra Guntuku View a PDF of the paper titled Effect of Static vs. Conversational AI-Generated Messages on Colorectal Cancer Screening Intent: a Randomized Controlled Trial, by Neil K. R. Sehgal and Manuel Tonneau and Andy Tan and Shivan J. Mehta and Alison Buttenheim and Lyle Ungar and Anish K. Agarwal and Sharath Chandra Guntuku View PDF Abstract:Large language model (LLM) chatbots show increasing promise in persuasive communication. Yet their real-world utility remains uncertain, particularly in clinical settings where sustained conversations are difficult to scale. In a pre-registered randomized controlled trial, we enrolled 915 U.S. adults (ages 45-75) who had never completed colorectal cancer (CRC) screening. Participants were randomized to: (1) no message control, (2) expert-written patient materials, (3) single AI-generated message, or (4) a motivational interviewing chatbot. All participants were required to remain in their assigned condition for at least three minutes. Both AI arms tailored content using participant's self-reported demographics including age and gender. Both AI interventions significantly increased stool test intentions by over 12 points (12.9-13.8/100), compared to a 7.5 gain for expert materials (p new | recent | 2025-07 Change to browse by: cs References & Citations NASA ADS Google Scholar Semantic Scholar export BibTeX citation Loading... BibTeX formatted citation × loading... Data provided by: Bookmark Bibliographic Tools Bibliographic and Citation Tools Bibliographic Explorer Toggle Bibliographic Explorer (What is the Explorer?) Connected Papers Toggle Connected Papers (What is Connected Papers?) Litmaps Toggle Litmaps (What is Litmaps?) scite.ai Toggle scite Smart Citations (What are Smart Citations?) Code, Data, Media Code, Data and Media Associated with this Article alphaXiv Toggle alphaXiv (What is alphaXiv?) Links to Code Toggle CatalyzeX Code Finder for Papers (What is CatalyzeX?) DagsHub Toggle DagsHub (What is DagsHub?) GotitPub Toggle Gotit.pub (What is GotitPub?) Huggingface Toggle Hugging Face (What is Huggingface?) ScienceCast Toggle ScienceCast (What is ScienceCast?) Demos Demos Replicate Toggle Replicate (What is Replicate?) Spaces Toggle Hugging Face Spaces (What is Spaces?) Spaces Toggle TXYZ.AI (What is TXYZ.AI?) Related Papers Recommenders and Search Tools Link to Influence Flower Influence Flower (What are Influence Flowers?) Core recommender toggle CORE Recommender (What is CORE?) Author Venue Institution Topic About arXivLabs arXivLabs: experimental projects with community collaborators arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs. Which authors of this paper are endorsers? | Disable MathJax (What is MathJax?)

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