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静态与对话式AI生成消息对结直肠癌筛查意愿的影响:一项随机对照试验
一项预注册随机对照试验纳入915名45-75岁、从未完成结直肠癌筛查的美国成年人,随机分为无消息对照、专家撰写患者材料、单条AI生成消息和动机式访谈聊天机器人四组,所有参与者需在分配条件下停留至少三分钟,两个AI组依据自报年龄和性别进行内容定制。结果显示,两种AI干预均使粪便检测意愿提升超过12分(12.9-13.8/100),而专家材料仅提升7.5分。
AI推荐理由 预注册随机对照试验(n=915,45-75岁未做过结直肠癌筛查的美国成年人),对比无消息对照、专家撰写材料、单条AI生成消息和动机式访谈聊天机器人四种条件,AI两组均使粪便检测意愿提升超过12分(12.9-13.8/100),专家材料仅提升7.5分。提供了LLM在临床说服场景的可验证量化证据,但摘要被截断,未给出完整统计显著性与效应量细节,且样本限于美国特定人群,外推需谨慎。
72
正文
Computer Science > Computers and Society
arXiv:2507.08211 (cs)
[Submitted on 10 Jul 2025]
Title:Effect of Static vs. Conversational AI-Generated Messages on Colorectal Cancer Screening Intent: a Randomized Controlled Trial
Authors:Neil K. R. Sehgal, Manuel Tonneau, Andy Tan, Shivan J. Mehta, Alison Buttenheim, Lyle Ungar, Anish K. Agarwal, Sharath Chandra Guntuku
View a PDF of the paper titled Effect of Static vs. Conversational AI-Generated Messages on Colorectal Cancer Screening Intent: a Randomized Controlled Trial, by Neil K. R. Sehgal and Manuel Tonneau and Andy Tan and Shivan J. Mehta and Alison Buttenheim and Lyle Ungar and Anish K. Agarwal and Sharath Chandra Guntuku
View PDF
Abstract:Large language model (LLM) chatbots show increasing promise in persuasive communication. Yet their real-world utility remains uncertain, particularly in clinical settings where sustained conversations are difficult to scale. In a pre-registered randomized controlled trial, we enrolled 915 U.S. adults (ages 45-75) who had never completed colorectal cancer (CRC) screening. Participants were randomized to: (1) no message control, (2) expert-written patient materials, (3) single AI-generated message, or (4) a motivational interviewing chatbot. All participants were required to remain in their assigned condition for at least three minutes. Both AI arms tailored content using participant's self-reported demographics including age and gender. Both AI interventions significantly increased stool test intentions by over 12 points (12.9-13.8/100), compared to a 7.5 gain for expert materials (p
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