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@Giulia Cisotto
利用VAE误差辅助基于ECG的心肌疤痕鉴别诊断
本研究评估了β-VAE衍生的ECG表示在鉴别心肌疤痕(LGE+)与无疤痕(LGE-)患者中的能力。在300名患者的本地队列中,使用ECGx.AI模型特征和浅层β-VAE进行比较,发现DTW重建误差在12导联中的10个导联上存在显著差异,有助于分类,但整体AUC最高仅0.686,表明其作为疤痕标志物的潜力有限。
AI推荐理由 探索基于VAE的ECG表示用于心肌疤痕鉴别诊断,但性能有限(AUC最高0.686),且样本量小(300例),属于医疗AI应用,对通用AI领域兴趣较低。
60
正文
计算机科学 > 机器学习
arXiv:2609.05294v1 (cs)
[提交于2026年9月4日]
标题:从VAE错误中学习以支持基于心电图的心肌瘢痕鉴别诊断
作者:Shayan Sharifi, Riccardo Treu, Ilaria Gandin, Federico Garoia, Marco Merlo, Giulia Cisotto
查看论文PDF,标题为“Learning from VAE Errors to support ECG-based Differential Diagnosis of Myocardial Scar”,作者Shayan Sharifi等5人
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摘要:心脏磁共振上的晚期钆增强(LGE)是心肌瘢痕的关键标志,但其有限的可及性促使常规心电图(ECG)筛查。我们评估了β-变分自编码器(VAE)衍生的ECG表示是否能在本地300名受试者队列中区分LGE+和LGE-心肌病患者。我们比较了来自基础this http URL模型的32维特征与在正常PTB-XL ECG上训练的较浅β-VAE的特征,评估了下游分类和基于动态时间规整(DTW)的重建误差。this http URL在随机森林下达到0.686的ROC曲线下面积,而所提出的β-VAE在梯度提升下达到0.577,灵敏度为0.775。值得注意的是,根据Mann-Whitney U检验,DTW重建误差在12个导联中的10个导联中在类别间显著不同,并有助于分类,导致逻辑回归下ROC曲线下面积为0.643,支持其作为瘢痕相关ECG改变标志物的潜力。
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机器学习 (cs.LG);机器学习 (stat.ML)
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arXiv:2609.05294 [cs.LG]
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arXiv:2609.05294v1 [cs.LG] 用于此版本)
https://doi.org/10.48550/arXiv.2609.05294
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来自:Shayan Sharifi [查看电子邮件]
[v1]
2026年9月4日星期五 15:46:18 UTC (834 KB)
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Computer Science > Machine Learning
arXiv:2609.05294v1 (cs)
[Submitted on 4 Sep 2026]
Title:Learning from VAE Errors to support ECG-based Differential Diagnosis of Myocardial Scar
Authors:Shayan Sharifi, Riccardo Treu, Ilaria Gandin, Federico Garoia, Marco Merlo, Giulia Cisotto
View a PDF of the paper titled Learning from VAE Errors to support ECG-based Differential Diagnosis of Myocardial Scar, by Shayan Sharifi and 5 other authors
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Abstract:Late Gadolinium Enhancement (LGE) on cardiac magnetic resonance is a key marker of myocardial scar, but its limited accessibility motivates routine ECG-based screening. We evaluated whether $\beta$-variational autoencoder (VAE)-derived ECG representations can discriminate LGE+ from LGE- cardiomyopathic patients in a local cohort of 300 subjects. We compared 32-dimensional features from the foundation this http URL model with those from a shallower $\beta$-VAE trained on normal PTB-XL ECGs, evaluating downstream classification and Dynamic Time Warping (DTW)-based reconstruction errors. this http URL reached an area under ROC of 0.686 with Random Forest, while the proposed $\beta$-VAE reached 0.577 with sensitivity of 0.775 with Gradient Boosting. Notably, DTW-reconstruction errors significantly differed between classes in 10 out of 12 leads according to Mann-Whitney U test and help in classification, leading to an area under ROC of 0.643 with Logistic Regression, supporting their potential as markers of scar-related ECG alterations.
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From: Shayan Sharifi [view email]
[v1]
Fri, 4 Sep 2026 15:46:18 UTC (834 KB)
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